Preparation and characterization of catechol-functionalized chitosan thermosensitive hydrogels

Autor:	P. W. Li, Z. Hu, S. T. Lu, Z. M. Yang, S. D. Li, D. Y. Zhang
Rok vydání:	2019
Předmět:	Chitosan chemistry.chemical_compound Catechol Chemistry Self-healing hydrogels Nuclear chemistry
Zdroj:	IOP Conference Series: Materials Science and Engineering. 629:012038
ISSN:	1757-899X 1757-8981
DOI:	10.1088/1757-899x/629/1/012038
Popis:	Catechol functionalization of chitosan was modified by EDC coupling reaction and then catechol-functionalized chitosan thermosensitive hydrogels were prepared by catechol-functionalization of chitosan with β-glycerophosphate disodium as a thermosensitizer. The hydrogels were then characterized by FTIR, 1H-NMR, SEM and rheology analysis. The results demonstrated that the thermosensitive hydrogels were prepared at 37°C within several minutes by mixing 2% catechol-functionalized chitosan with 30% β-glycerophosphate disodium at a ratio of 8:2, and these thermosensitive hydrogels with porous network structure were expected to be developed as biomedical materials with wide applications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0c5cc4409cbaac7751764bf9c71f78e5 https://doi.org/10.1088/1757-899x/629/1/012038 Zobrazit plný text záznamu