A Parallelism Between Blood Sugar, Blood Calcium and Blood Coagulability in Normal and Jaundiced Dogs

Autor: Harold N. Wright, Donald W. Cowan
Rok vydání: 1930
Předmět:
Zdroj: Experimental Biology and Medicine. 27:950-952
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-27-5055
Popis: It has been noted by many early observers, among them Wright,1 that the coagulation time of blood was decreased after meals. Schreiber2 and Kehr3 suggested the preoperative and postoperative use of intravenous glucose in obstructive jaundice, but it was not used extensively until Crile and Walters advocated it 5 years later. Partos and Svec4 pointed out that a relation existed between the sugar content and coagulability of the blood, namely, that with increasing blood sugar the clotting time is reduced. They demonstrated this effect following the injection of various substances which produce a hyperglycemia, e. g., glucose, epinephrine, theobromine sodium salicylate and morphine. Ravdin5 presented a series of experiments in which he attempted to justify the use of intravenous glucose in cases having lesions of the biliary apparatus and who were poor operative risks.In determining coagulation time we used 2 methods simultaneously in all cases, (1) that of Lee and White6 and (2) a modification of the method...
Databáze: OpenAIRE