ChemInform Abstract: A Facile and Highly Stereoselective Approach to a Polycyclic Isoindolinone Ring System via an N-Acyliminium Ion Cyclization Reaction

Autor: Christopher J. Northfield, Michael I. Page, Alexandra M. Z. Slawin, Steven M. Allin
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 29
ISSN: 1522-2667
0931-7597
DOI: 10.1002/chin.199839167
Popis: A highly diastereoselective synthesis of chiral ring-fused isoindolinone products, the skeleton of which is common to many naturally occurring and biologically active compounds, is achieved in only two synthetic steps from readily available precursors via an N-acyliminium ion cyclization reaction of an isoindolinone substrate.
Databáze: OpenAIRE