0352 A Large-Scale EEG Study at Home to Objectivise Effects of Ageing on Slow Wave Sleep and Process S
| Autor: | Clemence Pinaud, P J Arnal, K El Kanbi, L Artemis, T Trichet, Thorey, Eden Debellemaniere, A Chouraki |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Sleep. 43:A133-A134 |
| ISSN: | 1550-9109 0161-8105 |
| DOI: | 10.1093/sleep/zsaa056.349 |
| Popis: | Introduction Several studies have shown slow wave sleep (SWS) is altered with ageing. However, most of these studies have been conducted in-lab and usually over a single night. In this study, we assessed the evolution of process S with ageing by analysing the dynamics of endogenous and auditory-evoked slow waves in a large population. Methods 300 participants (200 M, 20 - 70 y.o.) were selected from volunteers users wearing a sleep headband for at least 3 nights, meeting the criteria of high signal quality and having no subjective sleep complaints nor being shift-workers. The Dreem headband is a connected device able to monitor EEG signals as well as pulse and movement and performs sleep staging in real-time automatically. Slow waves were detected as large negative deflections on the filtered EEG signals during NREM sleep. The auditory evoked slow waves were done using a previously validated closed-loop procedure. Results In our study, age was strongly correlated with N3 sleep duration (r=-0.34, p Conclusion These results confirmed the in-lab studies showing a heterogeneous alteration of homoeostatic process S with age, as well as a general decrease of slow wave occurrences, that is observed in parallel of a decrease of the probability of evoking slow waves, suggesting a global change in the system responsible for slow wave generation. Support This study was supported by Dreem sas and ANR, FLAG ERA 2015, HPB SLOW-Dyn |
| Databáze: | OpenAIRE |
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