Polyfunctional branched nitrogen-containing p-tert-butylthiacalix[4]arene derivatives as efficient agents for packaging calf thymus DNA
| Autor: | G. A. Evtugin, L. S. Yakimova, Ivan I. Stoikov, Joshua B. Puplampu |
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| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_element
Nanoparticle 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Nitrogen 0104 chemical sciences chemistry.chemical_compound Ultraviolet visible spectroscopy chemistry Dynamic light scattering Synthetic Receptors Polymer chemistry 0210 nano-technology Polyamine Dna packaging DNA |
| Zdroj: | Russian Chemical Bulletin. 66:1515-1523 |
| ISSN: | 1573-9171 1066-5285 |
| Popis: | Polyfunctional p-tert-butylthiacalix[4]arenes tetrasubstituted at the lower rim with nitrogen-containing fragments in the cone, partial cone, and 1,3-alternate conformations were investigated in the processes of calf thymus DNA packaging. The influence of the macrocycle structure and composition on their ability to pack DNA into nano-sized particles was considered. UV spectroscopy and dynamic light scattering results showed that the synthesized p-tert-butylthiacalix[4]arenes functionalized at the lower rim with polyamine fragments in the cone and 1,3-alternate conformations can compact calf thymus DNA into nanosized particles ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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