Cardiovascular responses of bluefish (Pomatomus saltatrix) to epinephrine, phentolamine and atropine

Autor: Stephen H. Fox, Arthur B. DuBois, Christopher S. Ogilvy
Rok vydání: 1992
Předmět:
Zdroj: Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 101:493-497
ISSN: 0306-4492
Popis: 1. Ventral aortic blood pressure and heart rate were recorded in bluefish (Pomatomus saltatrix) that were either unanesthetized or anesthetized with tricaine methanesulfonate. 2. Epinephrine caused a dose-related increase of blood pressure. The competitive inhibitor phentolamine inhibited the epinephrine response. 3. Phentolamine lowered the resting blood pressure indicating a tonic adrenergic influence on baseline vasomotor tone. Phentolamine had no significant effect on heart rate. 4. Atropine increased heart rate, as in other teleosts, indicating there had been vagal inhibition of the heart rate at rest. 5. These pharmacological studies demonstrate that bluefish have parasympathetic influence on heart rate and can respond to adrenergically mediated vasomotor tone as do other teleosts.
Databáze: OpenAIRE