Homocysteine in Occlusive Vascular Disease
| Autor: | Seema Bhargava |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pathology
medicine.medical_specialty Endothelium Homocysteine business.industry Smooth muscle layer Oxidative phosphorylation 030204 cardiovascular system & hematology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine.anatomical_structure chemistry medicine Platelet Lipid deposition Occlusive vascular disease business 030217 neurology & neurosurgery Organ system |
| Zdroj: | The Clinical Application of Homocysteine ISBN: 9789811076312 |
| DOI: | 10.1007/978-981-10-7632-9_3 |
| Popis: | Though homocysteine was first implicated in atherothrombosis, high circulating levels of it have a myriad pathologic effects including oxidative as well as molecular mechanisms in almost all organ systems. However, this section details how homocysteinemia causes and promotes atherothrombosis, starting with the initial event of disruption of the endothelium and going on to its varied effects on the circulating lipids, platelets, the endothelial functions (proteins and factors influencing dilatation and lipid deposition), smooth muscle layer and the adventitial layer of the vessel walls. |
| Databáze: | OpenAIRE |
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