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Introduction: Bronchiectasis (BR) is a chronic lung disease with abnormally dilated bronchi. It can lead to frequent hospital admissions, ICU stays and eventually to death. Aims and objectives: The aim of the study is to determine the microbiological and radiological distribution in BR patients and mortality associated with disease. Methods: Patients with ICD10 code J47 of BR between 1.1.2003 to 31.12.2015 were retrospectively evaluated using database of our hospital. 251 out of 470 patients confirmed with HRCT were included. Clinical data, radiological localization, sputum culture, hospitalizations and mortality were investigated. Results: 130 of 251 patients were female (51,7%).Mean age was 45 ±16 years. Sputum culture was available in 138 patients. Normal flora was detected in 65 (47%). P. aeruginosa was leading pathogen (38 patients-27,5%), followed by S.pneumoniae (9 patients-6,5%). In 28 (73,7%) of patients with P. aeruginosa , BR was bilateral. 29 (76,3%) of these patients were treated as inpatients, 8 of them had ICU admissions. 14 of 251 patients (5,6%) were dead in January 2016. The relation between smoking and mortality was statistically significant (p=0,024). P. aeruginosa and number of bacteria in sputum and ICU admissions were associated with mortality (p=0,0001). Higher number of lobes with BR were associated with mortality (p=0,036). Receiving COPD treatment was also associated with mortality (p=0,002). Conclusions: P.aeruginosa is the most common pathogen in sputum of BR patients, causing hospital and ICU admissions and its presence is strongly associated with mortality. Attempts to eradicate P. Aeruginosa in BR patients should be encouraged to lower the 5,6% mortality in these patients. |
