Near-Infrared Fluorescence Instrumentation for DNA Analysis

Autor: Jim L. Amen, Ramesh Raghavachari, Lyle R. Middendorf, Garrick Little, John Gewecke, Robert C. Bruce, Rex Peterson, John Rada, Abe Oommen, Harry Osterman, Steve Roemer, Dan Grone, Dan Draney, Nara Narayanan, Darryl DeGraff, Ananda G. Lugade, Pat G. Humphrey
Rok vydání: 1998
Předmět:
Zdroj: Near-Infrared Dyes for High Technology Applications ISBN: 9789401061438
DOI: 10.1007/978-94-011-5102-3_2
Popis: Information throughput relating to DNA analysis is enhanced by increasing sample channels (e.g., geometric, spectral, temporal discrimination), increasing information per sample channel (e.g., sequence read length, use of multiplexed loci), decreasing redundant information among samples, and decreasing time of sample preparation, data collection and processing. Recently, the use of solid-state optical components has provided a highly sensitive, yet economical detection system based on near-infrared (NIR) fluorescence. This is important for enhancing throughput for both electrophoresis-based automated analysis as well as for analysis using biochips and high density gridding.
Databáze: OpenAIRE