Evolution and Genetic Regulation of Complement C3 and C4 Genes

Autor: M. Nonaka, J.-H. Zengh, N Yamaguchi, S. Natsuume-Sakai, Morinobu Takahashi
Rok vydání: 1993
Předmět:
Zdroj: Progress in Immunology Vol. VIII ISBN: 9783642514814
Popis: Evidence has been accumulated that the complement system predated the immune system as the body defence mechanism in the vertebrates. Although the occurrence of immunoglobulines inducible by antigenic stimulation in the most primitive of the extant vertebrates has been widely accepted as a solid fact since the classical work of Marchalonis and Edelman (1968), more recent works conducted utilizing the techniques of molecular biology pointed to the other conclusion(Ishiguro et al. 1992).
Databáze: OpenAIRE