Epidemiology, risk factors and comorbidity for urinary tract infections caused by extended-spectrum beta-lactamase (ESBL)-producing enterobacteria
| Autor: | T. Palacios-Martín, P. Bachiller-Luque, M. González-Sagrado, M. Domínguez-Gil González, L. S. Briongos-Figuero, Antonio Dueñas-Laita, A. Gómez-Nieto, José Luis Pérez-Castrillón, T. Gómez-Traveso |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pediatrics
medicine.medical_specialty business.industry Urinary system Retrospective cohort study General Medicine Urine biochemical phenomena metabolism and nutrition Fosfomycin bacterial infections and mycoses medicine.disease Comorbidity Ciprofloxacin Internal medicine Diabetes mellitus Epidemiology Medicine business medicine.drug |
| Zdroj: | International Journal of Clinical Practice. 66:891-896 |
| ISSN: | 1368-5031 |
| DOI: | 10.1111/j.1742-1241.2012.02991.x |
| Popis: | Summary Aim: Urinary tract infection (UTI) caused by resistant bacteria is becoming more prevalent. We investigate characteristics and associated risk factors for UTIs resulting from extended-spectrum beta-lactamase (ESBL)-producing enterobacteria. Methods: Retrospective study of urinary tract isolates of ESBL-producing enterobacteria in adults (2009 and 2010). We included 400 patients and 103 controls (UTI caused by non-ESBL Escherichia coli). Clinical and demographic information was obtained from medical records. Comorbidity was evaluated using Charlson Index (CI). Strains were identified using VITEK 2 system. Results: A total of 400 isolates were obtained (93%E. coli and 7%Klebsiella spp). In 2009, 6% of cultures were ESBL-producing E. coli and 7% in 2010. 37% of patients were men and 81% were aged ≥ 60 years. CI was 2.3 ± 1.8 (high comorbidity: 42.8%). 41.5% of strains were susceptible to amoxicillin-clavulanate, 85.8% to fosfomycin and 15.5% to ciprofloxacin. The total number of ESBL E. coli positive urine cultures during hospital admission was 97 and, compared with 103 controls, risk factors for UTI caused by ESBL- E. coli strains in hospitalised patients were nursing home residence (p |
| Databáze: | OpenAIRE |
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