A cross-comparison between PMOD and HeartSee for absolute quantification of myocardial blood flow in PET imaging

Autor: Chuxin Zhang, Ruonan Wang, Yingqi Hu, Yanni Jia, Jun Zhang, Yuanyuan Li, Yanhui Wang, Xin Diao, Haitao Zhou, Ping Wu, Li Li, Yuetao Wang, Minfu Yang, Zhifang Wu, Sijin Li
Rok vydání: 2023
DOI: 10.21203/rs.3.rs-2525200/v1
Popis: Background: PMOD and the HeartSee software are commonly used to quantify myocardial perfusion. PMOD typically uses a one-tissue compartment model, whereas, HeartSee uses a simple retention model that is considered a special case of the one-tissue compartment model. We explored agreement in the absolute quantification of myocardial perfusion and the diagnostic performance of coronary microvascular dysfunction by comparison of PMOD and HeartSee in non-obstructive patients. Results: The rest myocardial blood flow of PMOD was higher than that of HeartSee (1.02±0.22 vs. 0.92±0.23, pvs.2.64±0.51, ppConclusions: The absolute quantification values obtained by PMOD and HeartSee were different. However, the diagnostic accuracy of HeartSee for abnormal myocardial flow reserve with a PET myocardial flow reserve less than two was 72%.
Databáze: OpenAIRE