The efficacy of on-demand sedation colonoscopy: a STROBE-compliant retrospective cohort study

Autor: Christopher Hang Liang Keh, Vincent Khor, Wei Chee Liew, Tian Fu Loh, Hung Leng Kaan, Shuo Ling Teo, Sze Wai Leong
Rok vydání: 2021
Předmět:
Zdroj: Surgical Endoscopy. 36:930-935
ISSN: 1432-2218
0930-2794
DOI: 10.1007/s00464-021-08351-y
Popis: Colonoscopy has been routinely performed with sedation. Previous studies showed that on-demand sedation colonoscopy is acceptable in patients. We aim to compare the clinical outcomes of patients undergoing colonoscopy with and without sedation. A prospectively collected retrospective matched cohort study was performed. 290 consecutive patients who underwent colonoscopy without sedation were included into the study. Another 290 patients who underwent colonoscopy with sedation were then selected based on matched sex and age group distribution. Data were collected in a prospective database. Age, sex, race, and procedural variables were collected. Outcomes analyzed included adenoma detection rate, Boston bowel preparation scores, time spent in the recovery room, cecal intubation time, and presence of pain during colonoscopy. A total of 580 patients were included in the study. Of the 290 patients who underwent colonoscopy without sedation, 10 patients (3.45%) required sedation to be administered to complete the scope. Intention-to-treat analysis was performed. Multivariate analysis demonstrated that the administration of sedation was a significant predictor of prolonged recovery time (increase in 34.76 min, 95% CI 29.56–39.55, p
Databáze: OpenAIRE
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