| Popis: |
Bone marrow examination forms an important part of the investigative repertoire of almost all haematological malignancies. The ease of performing a bone marrow biopsy, especially when compared to difficult to reach nodal sites or tricky organs like the spleen, makes bone marrow sampling an investigation of choice. Furthermore, this provides adequate and suitable material to perform the entire range of investigations, from rapid assessment using Giemsa stain to Next Generation Sequencing. Bone marrow examination has been a joint responsibility of haematologist and histopathologist with a wide variation in practise, not only in the UK but throughout the world. For many histopathologists, who are comfortable looking at lymph nodes, assessing bone marrow trephines, let alone aspirate morphology can seem daunting. This article aims to familiarize the reader with the basic structure and function of the bone marrow and normal morphology of haematopoietic cells. |
Full Text from ScienceDirect