Asymmetric Construction of 4H-Carbazol-4-one Intermediates via the Cyclohexadienone Annulation of Chiral Carbene Complexes

Autor:	Arnold L. Rheingold, Timothy S. Powers, Glenn P. A. Yap, John F. Quinn, William D. Wulff
Rok vydání:	1997
Předmět:	chemistry.chemical_classification Chiral auxiliary Annulation Atropisomer Imidazolidinone Organic Chemistry chemistry.chemical_element Alkyne Inorganic Chemistry Chromium chemistry.chemical_compound chemistry Product (mathematics) Polymer chemistry Physical and Theoretical Chemistry Carbene
Zdroj:	Organometallics. 16:4945-4947
ISSN:	1520-6041 0276-7333
DOI:	10.1021/om970639k
Popis:	The quaternary carbon in a 4H-carbazol-4-one can be introduced with high stereoprecision in the cyclohexadienone annulation of a 2-indolyl chromium carbene complex bearing an imidazolidinone chiral auxiliary. The chiral complex 12 was found to exist as atropisomers that were readily separated, and each was found to react with the same alkyne to give opposite configurations at the quaternary carbon in the 4H-carbazol-4-one product.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::02256745d6d530ad68429e4f2842de59 https://doi.org/10.1021/om970639k Zobrazit plný text záznamu