Inflammatory bowel disease in children: vitamin D status and specific features of the course of disease in its insufficiency
| Autor: | D.V. Pechkurov, A.V. Gorelov, E.V. Borisova, O.A. Savvateeva, A.M. Savvateev, S.D. Podimova, E.Yu. Polotnyanko |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Voprosy detskoj dietologii. 19:16-23 |
| ISSN: | 2414-9519 1727-5784 |
| DOI: | 10.20953/1727-5784-2021-1-16-23 |
| Popis: | Objctive. To substantiate and assess the efficacy of using vitamin D and polyunsaturated fatty acids in basic treatment of inflammatory bowel disease (IBD) in children. Patients and methods. We examined 108 patients aged 1 to 17 years with IBD, among them 59 boys (54.6%), 49 girls (45.4%). After assessment of vitamin D status, children with IBD were randomised into two groups, comparable by age, gender and nosological forms. Group D– comprised 54 patients who received only basic IBD therapy, group D+ consisted of 54 patients who received basic treatment and a combination of cholecalciferol and polyunsaturated fatty acids (PUFAs). The children were examined at 1 and 6 months after the beginning of therapy. The comparison group included 62 children of the corresponding age who belonged to the 1st–2nd health status groups. Results. As has been found, more than 90% of children with IBD have an insufficient vitamin D status (average level 17.9 ± 7.9 ng/ml, in the comparison group – 25.03 ± 8.2 ng/ml, р > 0.05). A quarter of children have a significant vitamin deficiency (levels of 25(ОН)D |
| Databáze: | OpenAIRE |
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