| Autor: |
Juan Chen, Wuling Liu, Babu Gajendran, Arpita Karandikar, Xiangchun Shen, Krishnapriya Madhu Varier, Yaacov Ben-David, Arulvasu Chinnasamy |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.1016/b978-0-12-821265-3.00018-9 |
| Popis: |
Various preclinical studies by researchers have established that there exist an inevitable relationship between the gut microbiota and neonatal brain development. This was further extrapolated to humans. This communication can be majorly through the regulation of the blood-brain barrier function as well as epithelial barrier, glial cell activation and its maturation plays a key role. The hormonal and neural directive through the hypothalamic-pituitary-adrenal axis (HPA axis), as well as modulation of immunity as well as metabolic activities along with neurotransmitter release, contributes to the other part. The researchers’ even link between the nutritional interventions of the mother hat can shape neurodevelopment in the modulation of the neonate’s microbiome. Thus, in this review, we present the importance of gut microbes and its diversified functions in neonatal brain development. We further emphasis on the reputation of the hormonal, immune as well as reproductive systems in the brain development by linking to the mother’s nutritional status. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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