Effect of Gestational Diabetes on Serum Leptin during Pregnancy and Postpartum Period

Autor:	Jazib Andleeb, Faiza Mehboob, Sana Javaid, Mudassar Ali, Muhammad Imran Khan, Qurat-ul-Ain
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Serum Insulin HOMA index endocrine system diseases Pregnancy nutritional and metabolic diseases Medicine Gestational diabetes mellitus Microbiology hormones hormone substitutes and hormone antagonists QR1-502 Serum Leptin
Zdroj:	The International Journal of Frontier Sciences, Vol 5, Iss 1 (2020)
ISSN:	2618-0367 2618-0359
Popis:	Background: Gestational diabetes mellitus (GDM) is associated with marked increase in insulin resistance. The objective of study is to determine the relation of gestational diabetes with serum leptin and serum insulin levels during pregnancy and postpartum period. Methods: This case control study conducted on total ninety samples that include cases and controls taken after 24 weeks of gestation. The case sample included 40 pregnant women with GDM and 10 women with GDM at postpartum stage. The control sample included 30 normal pregnant women with no GDM and 10 normal women at postpartum. Fasting serum leptin and fasting serum insulin were measured by ELISA. HOMA index was calculated by fasting serum insulin and fasting blood glucose. Results: Serum leptin (30.89 ± 1.35), serum insulin (27.67 ± 1.32) and HOMA index (8.33 ± 0.53) significantly high in gestational diabetic women than normal pregnant (p
Databáze:	OpenAIRE
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