Hormonal and adiposity state of women with polycystic ovary syndrome: implication of adiponectin and leptin

Autor: Aleksandra Atanasova Boshku, Sasha Jovanovska Mishevska, Beti Zafirova Ivanovska, Daniela Ivanova Panova
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Endocrine Oncology and Metabolism, Vol 2, Iss 4, Pp 242-249 (2016)
ISSN: 1849-9031
1849-8922
Popis: Obesity and insulin resistance are frequently seen comorbidities in patients with polycystic ovary syndrome (PCOS), affecting the already disturbed metabolism of these patients. Disturbed secretion of adiponectin and leptin could be one of the contributing factors of obesity and insulin resistance in patients with PCOS. The aim of this study was to determine the levels of adiponectin and leptin in PCOS patients, as well as their association with other components of the syndrome. This cross-sectional study determined clinical, hormonal, and biochemical markers in 61 women with PCOS and 56 controls. There was a statistically significant difference in adiponectin and leptin between the groups (p>0.001). There was a significant negative correlation between adiponectin, body mass index (BMI), and waist circumference (r= -0.478; -0.452, p
Databáze: OpenAIRE