Quality of Sleep in Bronchial Asthma and Factors Influencing It - A Cross-Sectional Study from a Tertiary Care Centre in West Rajasthan, India

Autor: Narendra U., Sandeepa H.S, Deepak U.G, K.C. Agarwal, Priyanka Rodrigues, Supriya Sandeepa
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Evidence Based Medicine and Healthcare, Vol 8, Iss 12, Pp 688-693 (2021)
ISSN: 2349-2570
Popis: BACKGROUND Several studies showed that quality of sleep is reduced in asthma, but majority of the studies have used subjective methods for assessment of quality of sleep. This study was carried out to objectively measure quality of sleep using various sleep parameters by polysomnography in asthmatics and compare these sleep parameters with level of asthma control and with severity of airway limitation. METHODS This is a cross sectional study conducted among 50 adult asthma patients. History of the patients was taken. Patients included in the study were assessed clinically for asthma control, spirometry and each one of them was subjected to overnight level 1 polysomnography. Level of asthma symptom control was done depending on the daytime symptoms, reliever usage, night awakenings and activity limitation. Level of asthma control and airway limitation, forced expiratory volume in 1 second (FEV1) were compared with various sleep parameters. Tukey's post hoc test was performed to check as to which specific independent variable level significantly differs from the other. RESULTS Among 50 patients, 32 were men, mean age of the study population was 46.04 years. Mean sleep efficiency of study population was 76 ± 10.34 %. Average apnoea-hypopnea index (AHI) of the population was 7.86 / hr. Arousal index was 13.22 / hr. and desaturation index was 11.46 / hr. in asthmatics. Uncontrolled asthma patients had lower sleep efficiency (67.05 ± 8.19 % vs. 83 ± 5.5 %), longer sleep onset latency (29.11 ± 5.48 min vs. 23.25 ± 6.2 min), higher AHI (15.03 ± 10.1 / hr. vs. 1.57 ± 0.6 / hr.), more frequent arousals (23.32 ± 13.4 / hr. vs. 3.31 ± 2.42 / hr.) and more desaturations (18.72 ± 7.76 / hr. vs. 1.66 ± 1.53 / hr.) compared to well controlled asthma patients. Similar correlation was found with severe airway limitation. CONCLUSIONS Sleep quality is reduced in asthmatics. Optimal management targeting good asthma control and preventing the airway limitation is the key to achieve good quality of sleep and good quality of life. Subjective assessment in the form of questionnaires can be used as screening tools to evaluate the sleep; polysomnography can be used for confirmation.
Databáze: OpenAIRE