Impact of HTST pasteurization of human milk on the kinetic of digestion of macronutrients after in vitro dynamic digestion
| Autor: | Sottemano, S., Maiocco, Giulia, Nebbia, Carlo Stefano, Giribaldi, Marzia, Ménard, Olivia, Dupont, Didier, DEGLAIRE, Amélie, Cavallarin, Laura, Coscia, Alexandra, Bertino, Enrico |
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| Přispěvatelé: | Neonatal Unit of the University, Partenaires INRAE, Institute of the Science of Food Production. CNR., Science et Technologie du Lait et de l'Oeuf (STLO), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Neonatal Unit of the University, City of Health and Science of Turin |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
cinétique de digestion
mesure d'impact Ingénierie des aliments lait humain pasteurisation nutrition santé humaine macronutriment allégations nutritionnelles et de santé Alimentation et Nutrition [SDV.IDA]Life Sciences [q-bio]/Food engineering Food engineering Food and Nutrition [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition |
| Zdroj: | 40th Congress of the Union of Middle-Eastern and Mediterranean Pediatric Societies 40th Congress of the Union of Middle-Eastern and Mediterranean Pediatric Societies, Oct 2019, Cagliari, Sardinia, Italy. 2019 2019; 40th Congress of the Union of Middle-Eastern and Mediterranean Pediatric Societies, Cagliari, Sardinia, ITA, 2019-10-24-2019-10-26 |
| Popis: | International audience; Introduction: Donor human milk (DHM) represents the best alternative when mother’s own milk is not available, a common occurrence in Neonatal Intensive Care Units. Heat treatment of DHM is mandatory for safety reasons. Holder pasteurization (HoP, 62.5°C-30’) is recommended by all human milk bank guidelines. Recent studies have demonstrated that HoP affects the digestion profile and behavior of several human milk components. High Temperature-Short Time pasteurization (HTST, 71°C-15’’) is currently under evaluation as a promising alternative technology to limit the denaturation of some biological compounds of raw human milk. The aim of the present work was to assess whether the different types of pasteurization (HoP, HTST) impacted the digestive kinetics of human milk during in vitro dynamic digestion. Materials and Methods: pooled raw HM (RHM) was collected and processed by using the two pasteurization techniques. The pasteurized samples and RHM were digested in vitro using preterm gastrointestinal conditions. Samples were collected at different digestion times. Undigested and digested milks samples were characterized for their particle size distribution (PSD), triglyceride content, protein and amino acid (AA) profiles. Results: during gastric digestion, both pasteurization methods modified PSD, as compared to RHM. Caseins were rapidly hydrolyzed in the gastric phase unlike that for the whey proteins. Lactoferrin was hydrolyzed faster in the pasteurized samples in comparison to RHM, in which lactoferrin was resistant to gastro-intestinal digestion. Heat-treatments, consequently, affected the intestinal release of some AA, and a higher bioaccessibility of AA was found for HTST, as compared to HoP. Concerning lipolysis, at any time of the intestinal digestion phase, the lipolysis of HoP samples was significantly lower (p < 0.05) than in both RHM and HTST samples. Conclusions: this work provides the first important evidences on the differential impact of HoP and HTST pasteurization techniques on bioaccessibility of DHM nutrients and biological compounds, for preterm newborns. |
| Databáze: | OpenAIRE |
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