| Autor: |
Peharda, V., Marija Kastelan, Cabrijan, L., Saftic, M., Gruber, F. |
| Jazyk: |
angličtina |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Scopus-Elsevier |
| Popis: |
Background. Tinea capitis is a common dermatomycosis in children. A number of systemic and topical agents can be used in treating tinea capitis. Terbinafine is a new allylamine agent highly effective against dermatophytes. Objective. The efficacy and tolerability of terbinafine in the treatment of tinea capitis in children was studied. Methods. A total of sixteen children with mycologically fungal infection caused by Microsporum canis were enrolled in the study. The patients´ age ranged from 6-12 (mean 8.3 years). Patients recevided 125 mg terbinafine daily for two months. Results. At the end of the trial 14 patients were evaluable: 13 with superficial infection and one case of Kerion. Clinical cure was achieved in 11 (78.5%) children. The drug was well tolerated with one patient reporting mild gastrointestinal problem. Conclusion. Our results indicate that terbinafine once daily is safe and well tolerated, but not always effective in the treatment of microsporosis capitis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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