Chronic obstructive cholestasis with gallbladder masses associated with invasive fungal infection in a preterm neonate: a case report
| Autor: | Anne Geurden, Anneleen Engelen, luisa vonghia, Nicolette Moes, Veerle Matheeussen, Bart Bracke, Koen Vanden Driessche, Ludo Mahieu |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Belgian Journal of Paediatrics University of Antwerp |
| ISSN: | 2566-1558 |
| Popis: | A preterm boy, born at the gestational age of 26 weeks, developed a sepsis followed by obstructive cholestasis at the age of 4 weeks despite broad spectrum antibiotic and fluconazole treatment. Abdominal ultrasound showed masses of unknown origin in the gallbladder. An invasive fungal infection was diagnosed via serum (1,3)-beta-D-glucan. After initiation of the echinocandin caspofungin, inflammation and cholestasis parameters subsided quickly and the patient recovered. Accumulation of fungal balls in the gallbladder has been described as a cause of chronic obstructive cholestasis in immunocompromised adults, this is the first reported case in a preterm neonate. |
| Databáze: | OpenAIRE |
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