Quality of Life in Young Patients After Bone Tumor Surgery Around the Knee Joint and Comparison With Healthy Controls
| Autor: | Bekkering, W.P., Vlieland, T.P.M.V., Koopman, H.M., Schaap, G.R., Schreuder, H.W.B., Beishuizen, A., Tissing, W.J.E., Hoogerbrugge, P.M., Anninga, J.K., Taminiau, A.H.M. |
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| Přispěvatelé: | Pediatrics, Other Research, Orthopedic Surgery and Sports Medicine, Faculteit Medische Wetenschappen/UMCG, Guided Treatment in Optimal Selected Cancer Patients (GUTS) |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
ROTATIONPLASTY
AMPUTATION bone tumor children malignant quality of life surgery childhood-cancer survivor congenital heart-disease adult survivors limb salvage children sarcoma amputation rotationplasty piedmont registry ADULT SURVIVORS CHILDREN bone tumor LIMB SALVAGE Quality of Care [ONCOL 4] surgery CONGENITAL HEART-DISEASE malignant quality of life REGISTRY CHILDHOOD-CANCER SURVIVOR SARCOMA PIEDMONT |
| Zdroj: | Pediatric Blood & Cancer, 54, 738-45 Pediatric Blood & Cancer, 54, 5, pp. 738-45 Pediatric Blood & Cancer, 54(5), 738-745 Pediatric Blood & Cancer, 54, 738-745. Wiley-Liss Inc. Pediatric blood & cancer, 54(5), 738-745. Wiley-Liss Inc. Pediatric blood & cancer, 54(5), 738-745. Wiley |
| ISSN: | 1545-5009 |
| Popis: | Contains fulltext : 89527.pdf (Publisher’s version ) (Closed access) BACKGROUND: This study aimed to compare the health related quality of life (HRQoL) of children and adolescents after malignant bone tumor surgery of the leg with healthy controls. PROCEDURE: Patients between 8 and 25 years old were cross-sectional recruited. Patients under 16 years of age received the TNO (Netherlands Organization for Applied Scientific Research) and AZL (Leiden University Medical Center) Children's Quality of Life Questionnaire (TACQOL), patients aged 16 years and older received the TNO-AZL Questionnaire for Adult's Quality of Life (TAAQOL) and the Short Form-36 (SF-36). Three age- and sex-matched normative random samples, drawn from large, nationwide studies, were used for the comparison with healthy controls. Patients were interviewed regarding their most important problems related to the disease and its treatment. RESULTS: Eighty-one patients with a mean age of 16.9 years (SD 4.2) were included (41 female). Limb sparing surgery was executed in 38 patients, ablative surgery in 43 patients. In comparison with healthy controls, patients had significantly poorer HRQoL within the domains autonomy and motor function of the TACQOL, gross motor function, cognitive functioning, daily functioning and sexuality of the TAAQOL, and physical functioning, role physical, general health, and the physical and mental component summary scales of the SF-36. Patients reported limitations in physical activities, participation in sports, and cosmetic aspects as the most detrimental consequences of their disease and its treatment. CONCLUSION: In children and adolescents who underwent surgery for a malignant tumor of the leg physical, functioning was significantly impaired as compared to healthy controls. 01 mei 2010 |
| Databáze: | OpenAIRE |
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