Panniculitis in a Woman With Opportunistic Pulmonary Coinfection by Pneumocystis jirovecii and Cryptococcus neoformans
| Autor: | Tedbirt, Billal, Duval-Modeste, Anne-Benedicte, Courville, Philippe, Dominique, Stéphane, Vera, Pierre, Regaieg, Hamza |
|---|---|
| Přispěvatelé: | Equipe Quantification en Imagerie Fonctionnelle (QuantIF-LITIS), Laboratoire d'Informatique, de Traitement de l'Information et des Systèmes (LITIS), Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Université Le Havre Normandie (ULH), Normandie Université (NU)-Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Normandie Université (NU) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
MESH: Humans
MESH: Middle Aged MESH: Fluorodeoxyglucose F18 [SDV]Life Sciences [q-bio] MESH: Cryptococcosis MESH: Cryptococcus neoformans MESH: Opportunistic Infections MESH: Positron Emission Tomography Computed Tomography MESH: Female MESH: Pneumocystis carinii MESH: Coinfection MESH: Treatment Outcome MESH: Pneumonia Pneumocystis |
| Zdroj: | Clinical Nuclear Medicine Clinical Nuclear Medicine, Lippincott, Williams & Wilkins, 2021, 46 (4), pp.e210-e211. ⟨10.1097/RLU.0000000000003420⟩ |
| ISSN: | 0363-9762 |
| DOI: | 10.1097/RLU.0000000000003420⟩ |
| Popis: | International audience; A 56-year-old woman, with history of psoriasis well controlled on ustekinumab, underwent 18F-FDG PET/CT to explore first onset of histologically proven skin panniculitis of unknown origin. PET/CT showed high uptake in panniculitis lesions in limbs and in a lung opacity suggestive of pneumonia. Based on PET/CT findings, a bronchoalveolar lavage revealed pulmonary coinfection by Pneumocystis jirovecii and Cryptococcus neoformans. Thus, hematogenous dissemination of infection was suspected as etiology of panniculitis. She was treated with fluconazole and trimethoprim-sulfamethoxazole, leading to total resolution of skin lesions. Posttherapeutic PET/CT showed complete metabolic response of skin and pulmonary lesions. |
| Databáze: | OpenAIRE |
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