Respiratory infections in elderly people

Autor: Chasqueira, Maria-Jesus, Paixão, Paulo, Rodrigues, Maria-Lúcia, Piedade, Cátia, Caires, Iolanda, Palmeiro, Teresa, Botelho, Maria-Amalia, Santos, Madalena, Curran, Martin, Guiomar, Raquel, Pechirra, Pedro, Costa, Inês, Papoila, Ana, Alves, Marta, Neuparth, Nuno
Přispěvatelé: NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Centro de Estudos de Doenças Crónicas (CEDOC)
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Popis: This work was supported by Foundation for Science and Technology (Fundacao para a Ciencia e Tecnologia - FCT, grant number PTDC/SAU-SAP/116563/2010) through Operational Competitiveness Programme (COMPETE) as part of the National Strategic Reference Framework. OBJECTIVE: the aim of this study was to analyze the etiology and clinical consequences of viral respiratory infections in 18 elderly care centers (ECC) in Lisbon, which housed a total of 1022 residents. METHODS: nasopharyngeal swabs were collected whenever an elderly had symptoms of acute respiratory infections (ARI). PCR and RT-PCR were performed for influenza A/B, human parainfluenza virus 1-4, adenovirus, human metapneumovirus (HMPV), respiratory syncytial virus (RSV), rhinovirus, enterovirus, human coronavirus and human Bocavirus (HBoV). Array cards for atypical bacteria were also used in severe cases. RESULTS: in total, 188 episodes of ARI were reported, being rhinovirus the most frequently detected (n=53), followed by influenza A(H3) (n=19) and HBoV (n=14). Severe infections were reported in 19 patients, 11 of which were fatal, Legionela pneumophila, rhinovirus, HMPV and RSV associated with these fatalities. Nine influenza strains were analyzed, all antigenically dissimilar from vaccine strain 2013/14. "Age", "HMPV" and "Respiratory disease" showed an association with severe infection. CONCLUSIONS: in this study an etiologic agent could be found in 60% of the acute respiratory episodes. These data provides information about the circulating viruses in ECC and highlights the importance of searching both viruses and atypical bacteria in severe ARI. publishersversion published
Databáze: OpenAIRE
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