Lapsed donors: an untapped resource
| Autor: | Schreiber, George B, Glynn, Simone A, Damesyn, Mark A, Wright, David J, Tu, Yongling, Dodd, Roger Y, Murphy, Edward L, Retrovirus Epidemiology Donor Study |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Hepatitis B Surface Antigens Time Factors Retrovirus Epidemiology Donor Study Liver Disease Clinical Sciences Immunology Age Factors HIV Infections Blood Donors Middle Aged Cardiorespiratory Medicine and Haematology Hepatitis C Hepatitis Emerging Infectious Diseases Infectious Diseases Good Health and Well Being Hepatitis - C Cardiovascular System & Hematology Clinical Research Prevalence Humans HIV/AIDS Digestive Diseases Infection |
| Zdroj: | Transfusion, vol 43, iss 1 Schreiber, GB; Glynn, SA; Damesyn, MA; Wright, DJ; Tu, YL; Dodd, RY; et al.(2003). Lapsed donors: an untapped resource. TRANSFUSION, 43(1), 17-24. doi: 10.1046/j.1537-2995.2003.00290.x. UCSF: Retrieved from: http://www.escholarship.org/uc/item/6mj3g5d8 |
| DOI: | 10.1046/j.1537-2995.2003.00290.x. |
| Popis: | BackgroundThere is a clear need for methods to recruit and retain donors without compromising blood safety. Although prior studies report lower viral prevalence rates in repeat donors than those in first-time donors, it is unknown if this relationship holds after a lapse of several years between donations.Study design and methodsA total of 6.4 million allogeneic donations collected at five US blood centers from 1991 through 1998 were classified by donation history (first-time vs. repeat) and by length of time between donations (lapsed interval length). The prevalence of HCV, HIV, and HBsAg was compared by donation history and lapsed interval length. The relationship between lapsed interval length and donor demographics was explored.ResultsRepeat donors who delayed their return for over 5 years were significantly less likely to test positive for a viral infection than were first-time donors. The likelihood of a positive test result appeared to increase steadily with lapsed interval length for HCV and HBsAg, but not for HIV. Younger, less educated, and nonwhite donors were less likely to return than others.ConclusionsRecruitment of donors who have not returned for several years could be an effective way to increase the blood supply while preserving blood safety. Understanding the relationship of donor demographics to return behavior is important for recruitment efforts. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|