Protective effects of aqueous extract of Citrullus lanatus fruit on reproductive functions and antioxidant activities in arsenic-treated male wistar rats
| Autor: | Daramola, O. O., Wahab Oyeyemi, Beka, F. U., Ofutet, E. A. |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | African Journal of Biomedical Research; Vol 21, No 1 (2018); 65-72 Scopus-Elsevier |
| ISSN: | 1119-5096 |
| Popis: | Arsenic trioxide (As2O3), a known male reproductive toxicant induces it effects majorly through oxidative stress. Citrullus lanatus fruit is widely consumed for its high medicinal values and antioxidant capacities. This study investigated the effects of aqueous extract of Citrullus lanatus fruit (AECL) on reproductive functions and antioxidant activities in arsenic-treated male Wistar rats. Thirty male Wistar rats (150-190 g) were grouped into six and treated as follows; Control, 3 mg/kg As2O3, 100 mg/kg AECL, 200 mg/kg AECL, As2O3+100 mg/kg AECL and As2O3+200 mg/kg AECL. All administration was done orally for thirty days. Caudal sperm, serum hormone levels and testicular antioxidant activities were evaluated. Decreases (p |
| Databáze: | OpenAIRE |
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