Clinical Profile and Outcome of Severe Sepsis Related Acute Kidney Injury Among Patients Admitted in Intensive Care Unit – An Observational Prospective Study
| Autor: | Chandar, S., Pandurangan, V., Madhavan, S., Srinivasan, D., Bhaskar, E., Marappa, L., PRIYADARSHINI VARADARAJ, Nair, A. M., Rajendran, V. |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Online Journal of Health & Allied Sciences, Vol 20, Iss 1 (2021) Scopus-Elsevier |
| ISSN: | 0972-5997 |
| Popis: | Background: Critically ill patients in Intensive care unit (ICU) are at a high risk of developing Acute Kidney Injury (AKI) and sepsis is attributed as a cause for AKI in almost half of them. Sepsis related AKI (S-AKI) causes 6 to 8 fold increase in mortality. Aim: To study the clinical profile and outcome of patients with severe sepsis related AKI and to assess the factors associated with fatal outcome among those patients. Methods: This study was a prospective observational design done over a period of 18 months among patients admitted in ICU in a tertiary care hospital in South India. Patients above 18 years of age satisfying case definition of severe sepsis, who had AKI or developed AKI were studied. During their course of stay, timing of onset of AKI, primary source of infection, need for ventilatory support and renal replacement therapy (RRT) were noted. Outcome was categorized as survivors and non-survivors and factors associated with mortality was assessed. Results: Among the total 304 patients studied, 68.1% (n=207) were males and 31.95 (n=97) were females. Mean AKI onset was 1.62 days with 80% having onset |
| Databáze: | OpenAIRE |
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