| Autor: |
Tollenaar, L.S.A., Lopriore, E., Middeldorp, J.M., Haak, M.C., Klumper, F.J.C.M., Oepkes, D., Slaghekke, F. |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Ultrasound in Obstetrics and Gynecology |
| Popis: |
OBJECTIVE:To investigate the predictive value of delta middle cerebral artery - peak systolic velocity (MCA-PSV) > 0.5 multiples of the median (MoM) compared to cut-off MCA-PSV values (>1.5 MoM in the donor, < 1.0 MoM in the recipient) for the diagnosis of twin anemia polycythemia sequence (TAPS).METHODS:Retrospective consecutive cohort study comprising consecutive uncomplicated monochorionic twins and twins with postnatal TAPS between 2003 and 2017 in the Dutch national referral center for fetal therapy. We compared the accuracy to predict postnatal TAPS between the current method using the specific MCA-PSV cut-off values (>1.5 MoM in the donor and 0.5 MoM.RESULTS:In total, 45 uncomplicated monochorionic and 35 TAPS twins were analyzed. The sensitivity and specificity of the cut-off MCA-PSV values (>1.5 MoM, 0.5 MoM, but did not reach both the cut-off MCA-PSV levels (>1.5 MoM, CONCLUSION:Delta MCA-PSV > 0.5 MoM has a higher diagnostic accuracy for predicting TAPS compared to the currently used MCA-PSV cut-off values. We therefore propose a new antenatal classification system. In case of a delta MCA-PSV > 0.5 MoM on Doppler ultrasound, but with normal MCA-PSV values in donor or recipient, obstetricians should be aware of the therapeutic implications and neonatal morbidities associated with TAPS. This article is protected by copyright. All rights reserved. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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