Unusual 2(1H)-Pyrazinones Isolated from a Culture of a Brazilian Marine-Derived Streptomyces sp

Autor:	Thomasi, Sergio S., Granato, Ana C., Romano, Luis H., Dhooghe, Liene, Do Nascimento, Eduardo S. P., Badino, Alberto C., Da Silva, Maria F. G. F., Ferreira, Antonio G., Tiago Venâncio
Předmět:	Pharmacology. Therapy
Zdroj:	ResearcherID Web of Science NATURAL PRODUCT COMMUNICATIONS
ISSN:	1934-578X
Popis:	Four new secondary metabolites, giovaninones A-D (1-4), were isolated from an ethyl acetate extract of a culture of a marine-derived Streptomyces strain designated SS99BA-2. Chemical analysis was completely conducted in a coupled automated LC-SPE system with the use of a cryogenic NMR probehead and FIRMS. The application of this system to identify, purify and elucidate all the structures is described.
Databáze:	OpenAIRE
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