The burden of multiple myeloma: Assessment on occurrence, outcomes and cost using a retrospective longitudinal study based on administrative claims database
| Autor: | Portu, S., Fanin, R., Patriarca, F., Morsanutto, A., Tosolini, F., Esti, R., Lorenzo Giovanni Mantovani |
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| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Scopus-Elsevier Italian Journal of Public Health; Vol 8, No 4 (2011): Cancer: from prevention to therapy Italian Journal of Public Health, Vol 8, Iss 4 (2011) |
| ISSN: | 1723-7815 1723-7807 |
| Popis: | Objective: Multiple myeloma (MM) is a malignancy of plasma cells that results in an overproduction of light and heavy chain monoclonal immunoglobulins. Multiple myeloma imposes a significant economic and humanistic burden on patients and society. The present study is aimed at assessing the burden of multiple myeloma in both epidemiologic and economic terms.Methods: A retrospective, naturalistic longitudinal study on the occurrence, outcome and cost of multiple myeloma using an administrative database, was performed. We selected residents of a North-eastern Region of Italy, who had their first hospital admission for multiple myeloma during the period 2001-2005. This group was followed up until 31-12-2006, death or transfers to other regional health services. Direct medical costs were quantified within the perspective of the Regional Health Service.Results: During the period 2001-2005, out of a population if 1.2 million inhabitants, we observed 517 incidents of patients diagnosed with MM (52% female). During the period of observation, 364 (70.4%) subjects died. Total health care costs per patient over the maximum of follow-up were estimated to be 76,630 Euro for subjects younger than 70 years old and 22,892 Euro in the older group.Conclusions: Multiple myeloma imposes a significant epidemiological and economic burden on the healthcare system. |
| Databáze: | OpenAIRE |
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