Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist

Autor: Grootscholten, C., Ligtenberg, G., Derksen, R.H.W.M., Schreurs, K.M., Glas-Vos, J.W. de, Hagen, E.C., Wall Bake, A.W. van den, Huizinga, T.W.J., Hoogen, F.H.J. van den, Bijl, M., Houwelingen, J.C. van, Snoek, F.J., Berden, J.H.M.
Přispěvatelé: Medical Psychology, Medical psychology, APH - Health Behaviors & Chronic Diseases, APH - Mental Health
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Zdroj: Quality of life research, 12(6), 635-644. Springer Netherlands
Quality of Life Research, 12(6), 635-644. Springer Netherlands
Quality of Life Research, 12, 635-44
Grootscholten, C, Ligtenberg, G, Derksen, R H W M, Schreurs, K M G, De Glas-Vos, J W, Hagen, E C, Van Den Wall Bake, A W L, Huizinga, T W J, Van Den Hoogen, F H J, Bijl, M, Van Houwelingen, J C, Snoek, F J & Berden, J H M 2003, ' Health-related quality of life in patients with systemic lupus erythematosus : Development and validation of a lupus specific symptom checklist ', Quality of Life Research, vol. 12, no. 6, pp. 635-644 . https://doi.org/10.1023/A:1025176407776
Quality of Life Research, 12, 6, pp. 635-44
ISSN: 0962-9343
DOI: 10.1023/A:1025176407776
Popis: Item does not contain fulltext Reliable and sensitive measures are needed to evaluate the quality of life (QoL) in patients with systemic lupus erythematosus (SLE). No lupus specific questionnaires are available. This study describes the development and validation of a disease-specific questionnaire for lupus patients, which assesses the presence and burden of 38 disease- and treatment-related symptoms: the SLE Symptom Checklist (SSC). Reliability and reproducibility were tested in respectively 87 and 28 stable SLE patients. The internal consistency (Cronbach's alpha coefficients 0.89) and test-retest reliability (Pearson product-moment correlation coefficient between 0.67 and 0.87) were satisfactory. Concurrent validity was supported by significant, but moderate correlations with other measures of subjective well-being and functional status. Responsiveness was measured in 17 patients with lupus nephritis treated with cyclophosphamide, at start of therapy and 1 year thereafter. A significant change in number of symptoms and total distress level was found. It is concluded that the SSC has satisfactory psychometric properties and appears suitable for both clinical and research purposes.
Databáze: OpenAIRE
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