Diagnosis-to-ablation time in atrial fibrillation: A modifiable factor relevant to clinical outcome

Autor: Bisbal, F, Alarcon, F, Ferrero-De-Loma-Osorio, A, Gonzalez-Ferrer, JJ, Alonso-Martin, C, Pachon, M, Valles, E, Cabanas-Grandio, P, Sanchez, M, Benito, E, Sarrias, A, Ruiz-Granell, R, Perez-Villacastin, J, Vinolas, X, Arias, MA, Marti-Almor, J, Garcia-Campo, E, Fernandez-Lozano, I, Villuendas, R, Mont, L
Rok vydání: 2019
Předmět:
Zdroj: JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Journal of Cardiovascular Electrophysiology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
ISSN: 1045-3873
1540-8167
Popis: Introduction Recurrences after atrial fibrillation (AF) ablation are still common. Among the reported clinical and imaging predictors of recurrences, diagnosis-to-ablation time (DAT) has been defined as a predictor of ablation outcome in single-center studies. We aimed to validate DAT in a multicenter real-life cohort. Methods This was a multicenter study including consecutive patients undergoing first paroxysmal and persistent AF ablation with radiofrequency or cryoballoon catheters during 2013. Cox proportional hazard regression models were performed to identify predictors of recurrence. Results In total, 309 patients were included across nine centers (71% men, 57 +/- 10 years old, 46% with hypertension, and 66% with CHA(2)DS(2)-VASc 1 year (P = .007), and LA diameter (P = .026) as independent predictors for AF recurrence. DAT > 1 year was the only modifiable factor independently associated with recurrence (HR 4.2 [95% CI, 1.5-11.9]) Conclusion Diagnosis-to-ablation time is a modifiable factor independently associated with recurrent arrhythmia and repeat ablation after first AF ablation. An early intervention strategy during the first year from AF diagnosis might improve outcomes.
Databáze: OpenAIRE
Externí odkaz: