Identification of genes expressed preferentially in the honeybee mushroom bodies by combination of differential display and cDNA microarray11Nucleotide sequence data reported are available in the DDBJ/EMBL/GenBank database under the accession numbers AB072427, AB072428 and AB072429

Autor: Takeuchi, Hideaki, Fujiyuki, Tomoko, Shirai, Kenichi, Matsuo, Yuko, Kamikouchi, Azusa, Fujinawa, Yumi, Kato, Azusa, Tsujimoto, Atsumi, Kubo, Takeo
Jazyk: angličtina
Předmět:
Zdroj: FEBS Letters. (2-3):230-234
ISSN: 0014-5793
DOI: 10.1016/S0014-5793(02)02319-0
Popis: To clarify the molecular basis underlying the neural function of the honeybee mushroom bodies (MBs), we identified three genes preferentially expressed in MB using cDNA microarrays containing 480 differential display-positive candidate cDNAs expressed locally or differentially, dependent on caste/aggressive behavior in the honeybee brain. One of the cDNAs encodes a putative type I inositol 1,4,5-trisphosphate (IP3) 5-phosphatase and was expressed preferentially in one of two types of intrinsic MB neurons, the large-type Kenyon cells, suggesting that IP3-mediated Ca2+ signaling is enhanced in these neurons.
Databáze: OpenAIRE