A short peptide capable of self-replicating while absorbed on mineral surfaces

Autor: Cachinero Padilla, José Carlos
Přispěvatelé: Prado Gotor, Rafael, Universidad de Sevilla. Departamento de Química Física
Rok vydání: 2018
Předmět:
Zdroj: idUS. Depósito de Investigación de la Universidad de Sevilla
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Popis: A single small peptide (from 5 to 9 residues long) is one of the finest candidates for being the first replicator that appeared on the primitive Earth and ultimately led to the emergence of life. However, it is not recognized as so, and replication-first theories tend to automatically disregard very small peptides as possible replicators. Their small size makes them seem unable to efficiently store and replicate information, but this might just be a false impression. In this dissertation, a hypothetical self-replication mechanism that can be carried out by a small peptide is presented and it shows that only a slight selectivity and catalytic activity are needed for replication to take place, even if many errors are made along the self-replication process. The fundamental role of minerals is also underlined as they could catalyze certain chemical reactions and provide the appropriate conditions that allow this small peptide to self-replicate. Universidad de Sevilla. Grado en Farmacia
Databáze: OpenAIRE