Urine markers of kidney disorders and their risk associations in HIV-Infected patients attending Nyanza Provincial General Hospital in Kisumu, Western Kenya

Autor: Opiyo, WO, Ng'wena, AGM, Ofulla, VO
Jazyk: angličtina
Rok vydání: 2012
Zdroj: East African Medical Journal; Vol 87, No 12 (2010); 495-501
ISSN: 0012-835X
Popis: Objective: To identify abnormal levels of urine metabolites and cells that serve as markers of existing kidney disorders in ambulatory HIV-infected patients.Design: A cross sectional study.Setting: Nyanza Provincial General Hospital’s patient support centre.Subjects: A total of 593 HIV infected patients were studied.Intervention: Dipstick urinalysis test was used to screen mid stream urine to detect constituents with altered levels.Results: Out of the 593 participants, the urine of 214 (36.1%) had abnormally altered levels of urine constituents, with more females afflicted than males [41.5% vs. 27.8%; OR 1.84 (1.28-2.63), χ2= 11.08, p=0.0009]. Urobilinogen was the most common urine metabolite while ketones were least commonly present. More participants had altered levels of leucocytes than erythrocytes in urine. Patients with pyuria were three times more likely to have elevated erythrocytes in their urine as well ( χ2= 34.37, p
Databáze: OpenAIRE