Anti-proliferative effect of Scoparia dulcis L. against bacterial and fungal strains
| Autor: | Coulibaly, AY, Konate, K, Youl, ENH, Sombie, PAED, Kiendrebeogo, M, Meda, N-T R, Lamien, A, Zeba, B, Nacoulma, OG |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Zdroj: | International Journal of Biological and Chemical Sciences; Vol 6, No 6 (2012); 3055-3063 |
| ISSN: | 1991-8631 1997-342X |
| Popis: | Scoparia dulcis L. was sequentially extracted with hexane, chloroform and methanol and soaked with aqueous-acetone (80%) to check for its antimicrobial activities against five bacterial and four fungal strains.250μg of each extract loaded on a whatman paper disc exhibited significant antimicrobial activities on all the fungus and against Gram-negative and Gram-positive bacteria. Therefore, P. mirabilis is less sensitive to all the extracts while B. cereus, a â-lactamase producer bacterium, was resistant to the activity of the polar methanol and aqueous-acetone extracts. By the microdilution method, the most active extracts were chloroform extract on B. cereus with minimal inhibitory concentration (MIC) of 1.56 mg/ml and Aqueous-acetone extract on S. typhimurium (MIC = 1.56 mg/ml); the antifungal activity was strongest for hexane extract (MIC = 6.25 mg/ml) on both A. niger and P. roquefortii.Keywords: Scoparia dulcis, Antibacterial, Antifungal, Polyphenols. |
| Databáze: | OpenAIRE |
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