| Popis: |
Aim: The aim of this pilot clinical study was to assess efficacy and predictability of dentin particulate autograft as regenerative treatment for alveolar ridge augmentation and two stage implant placement using CBCT radiographic analysis. Materials and methods: The sample of presented study consisted of 8 patients, with insufficient width of alveolar ridge in lateral lower jaw. After surgical removal of third molar or periodontally compromised tooth, a dentin autograft was prepared according to manufacturer recommendations. Clean extracted teeth were dried and ground in a sterile chamber of the Smart Dentin Grinder® unit (KometaBio Inc., Cresskill, USA). The particulate teeth were immersed in a basic alcohol cleanser to dissolve all organic remnants and bacteria and dehydrated. The particles were rinsed twice with sterile phosphate-buffered saline solution. The platelet- rich fibrin (PRF) membranes were prepared. Graft material was used for ridge augmentation and covered with PRF membranes. After 5 months of healing CBCT scan were made. During implants placement homogeneous integration of dentin particulate was found. Dental implants (BEGO Semados® SC BEGO, Germany) were inserted and restored by titanuim abutment and zirconia crown. Results: Clinical re-entry, pripor to dental implants placement confirmed a homogeneous integration of dentin autograft and bone-like appereance in former grafted area. Six months after implants placement CBCT scans were obtained as part of the standard procedure. The radiographic images of the target areas revealed no grafted bone resorption around the implants. All patients were followed for 6, 12 and 24 months after loading through clinical follow-ups and control CBCT scans. No resorption of the autograft arround inserted implants were found. Conclusion: Within its limitation, the present pilot clinical study revealed that autologous dentin particulate autograft may serve as an alternative autologous bone substitute to support alveolar ridge augmentation and two-stage implant placement. |
