| Autor: |
Saltović, Ema, Kovačević Pavičić, Daniela, Braut, Alen, Muhvić Urek, Miranda |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
Introduction. Candida-associated denture stomatitis (CADS) is an infection caused by Candida spp. which affects 60%-65% of denture wearers. It has complex and multifactorial aetiology and is often associated with the host’s immunodeficient conditions. Scientific evidence suggests that vitamin D has a potential immunomodulatory and anti-inflammatory effect. Objectives. The aim of this study was to measure the serum level of vitamin D in patients with CADS and estimate the relation between vitamin D deficiency and CADS occurrence. Materials and methods. The study involved 32 complete denture wearers with CADS and 32 control subjects without CADS that were sex- and age-matched. The subjects were clinically examined and the severity of CADS was evaluated according to Newton's classification scale. The level of vitamin D in the serum was determined by using the electrochemiluminescence assay. Results. In the CADS group, vitamin D level was 54.68±17.07 nmol/L and in the control group 56.82±17.75 nmol/L. No statistically significant difference was found between the groups (p=0.622). Vitamin D level was not in the correlation with the severity of denture stomatitis (rs=0.11 ; p>0.05). Conclusion. Vitamin D level is not a significant factor that can be associated with CADS and does not promote host’s susceptibility to CADS. The results indicate that a routine determination of vitamin D level in patients with CADS is not necessary. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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