| Autor: |
Ki Wong, Fung, Burgess, John, Nordenskjöld, Magnus, Larsson, Catharina, Tean Teh, Bin |
| Zdroj: |
Seminars in Cancer Biology; August 2000, Vol. 10 Issue: 4 p299-312, 14p |
| Abstrakt: |
The recent cloning of the gene responsible for multiple endocrine neoplasia type 1 (MEN 1) has opened new avenues for both clinical and basic science research in the field of endocrine oncology. A large amount of genetic information, particularly those in relation to germline and somatic mutations, has since been published during the last 2 years. This new knowledge has provided important insights into its gene function. The significance of these advances in relation to clinical management and future directions for research is discussed. |
| Databáze: |
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