| Autor: |
Guyot, K., Follet-Dumoulin, A., Lelie`vre, E., Sarfati, C., Rabodonirina, M., Nevez, G., Cailliez, J. C., Camus, D., Dei-Cas, E. |
| Zdroj: |
Journal of Clinical Microbiology; October 2001, Vol. 39 Issue: 10 p3472-3480, 9p |
| Abstrakt: |
ABSTRACTCryptosporidium parvumis usually considered the agent of human cryptosporidiosis. However, only in the last few years, molecular biology-based methods have allowed the identification ofCryptosporidiumspecies and genotypes, and only a few data are available from France. In the present work, we collected samples of whole feces from 57 patients from France (11 immunocompetent patients, 35 human immunodeficiency virus [HIV]-infected patients, 11 immunocompromised but non-HIV-infected patients) in whomCryptosporidiumoocysts were recognized by clinical laboratories. A fragment of the Cryptosporidium18S rRNA gene encompassing the hypervariable region was amplified by PCR and sequenced. The results revealed that the majority of the patients were infected with cattle (29 of 57) or human (18 of 57) genotypes ofCryptosporidium parvum. However, a number of immunocompromised patients were infected with C. meleagridis(3 of 57), C. felis(6 of 57), or a new genotype of C. muris(1 of 57). This is the first report of the last three species of Cryptosporidiumin humans in France. These results indicate that immunocompromised individuals are susceptible to a wide range ofCryptosporidiumspecies and genotypes. |
| Databáze: |
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