Long-term protective immune response elicited by vaccination with an expression genomic library of Toxoplasma gondii.

Autor: Fachado, Alberto, Rodriguez, Alexandro, Molina, Judith, Silvério, Jaline C, Marino, Ana P M P, Pinto, Luzia M O, Angel, Sergio O, Infante, Juan F, Traub-Cseko, Yara, Amendoeira, Regina R, Lannes-Vieira, Joseli
Zdroj: Infection and Immunity; September 2003, Vol. 71 Issue: 9 p5407-11, 5p
Abstrakt: Immunization of BALB/c mice with an expression genomic library of Toxoplasma gondii induces a Th1-type immune response, with recognition of several T. gondii proteins (21 to 117 kDa) and long-term protective immunity against a lethal challenge. These results support further investigations to achieve a multicomponent anti-T. gondii DNA vaccine.
Databáze: Supplemental Index