| Autor: |
Escola, J.M., Moreno, E., Chavrier, P., Gorvel, J.P. |
| Zdroj: |
Biochemical and Biophysical Research Communications; September 1994, Vol. 203 Issue: 2 p1230-1236, 7p |
| Abstrakt: |
LPS is the most important antigen of Brucellabacteria which are gram-negative facultative intracellular pathogens infecting a large proportion of animals and humans in the world. In order to get insights into the immune response mechanisms monitored by Brucella, its LPS was used as a model antigen. S-LPS, R-LPS, lipid A and O-chain purified from Brucella abortuswere tested in their capacity of inducing SDS-resistant MHC class II molecules after incubation with murine B lymphoma cells. S-LPS and O-chain gave a significant response sugesting that O-chain might induce an association with class II itself or might act as a carrier for antigens to bind MHC class II molecules. |
| Databáze: |
Supplemental Index |
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