A 500-kb Physical Map and Contig from the Harveyras-1Gene to the 11p Telomere

Autor: Russell, Mark W., Munroe, David J., Bric, Eva, Housman, David E., Dietz-Band, Jeanne, Riethman, Harold C., Collins, Francis S., Brody, Lawrence C.
Zdroj: Genomics; July 1996, Vol. 35 Issue: 2 p353-360, 8p
Abstrakt: A contiguous physical map was constructed from the Harvey ras-1 (HRAS1) gene to the 11p telomere. The contig spans approximately 500 kb and is minimally composed of a telomere-containing YAC and P1 and cosmid clones. Included in the contig are 11 sequence-tagged sites derived from P1 and cosmid ends. Three genes were placed on the contig in the following order: telomere–ribonuclease/angiogenin inhibitor (RNH)–Harveyras-1(HRAS1)–HRAS1-related complex (HRC). Two novel tetranucleotide repeats (heterozygosity of 66 and 68%) and a complex CA repeat (heterozygosity of 78%) were isolated and characterized.
Databáze: Supplemental Index