Absence of ABL1exon 2-encoded SH3 residues in BCR::ABL1destabilizes the autoinhibited kinase conformation and confers resistance to asciminib

Autor: Leyte-Vidal, Ariel, DeFilippis, RosaAnna, Outhwaite, Ian R., Kwan, Isabelle, Lee, Ji Young, Leavitt, Carlyn, Miller, Kaeli B., Rea, Delphine, Rangwala, Aziz M., Lou, Kevin, Patel, Suhana, Alvarez, Ailin, Shokat, Kevan M., Bahar, Ivet, Seeliger, Markus A., Shah, Neil P.
Zdroj: Leukemia; 20240101, Issue: Preprints p1-5, 5p
Databáze: Supplemental Index