Scleromyxedema in an adult following Sinopharm BBIBP-CorV vaccination: An extremely rare phenomenon

Autor: Parsaei, Amirhossein, Rezaei, Somayeh Sadat, Rahmani, Alireza, Masoumi, Maryam, Dehghanbanadaki, Hojat, Norouzi, Somayyeh, Riyahi, Mohammad Mehdi, Tabaraii, Reihane, Montazeri, Seyed Mohammad Hashem
Zdroj: Journal of Scleroderma and Related Disorders; June 2023, Vol. 8 Issue: 2 pNP9-NP12, 4p
Abstrakt: Introduction: The Sinopharm BBIBP-CorV vaccine produces a variety of cutaneous adverse effects. Scleromyxedema is a mucinous connective tissue disorder that causes skin thickness and sclerodermoid changes. According to our findings, this is the first case of scleromyxedema induced by the Sinopharm immunization.Case description: We discuss the case of a 75-year-old woman who acquired progressive thickening of the skin in her limbs and trunk after getting the Sinopharm vaccination. Examination, laboratory testing, and a biopsy were used to verify scleromyxedema diagnosis. Intravenous immunoglobulins, mycophenolate mofetil, and prednisolone were used in the treatment of the patient. The outcomes from the 4-month follow-up were reassuring.Conclusion: This study emphasizes the need of considering scleromyxedema as a connective tissue pathology in patients who have recently received Sinopharm vaccine and have similar cutaneous signs.
Databáze: Supplemental Index