| Abstrakt: |
Intact leucocyte function is essential for the body’s defense against infection. Any depression of leucocyte migration, phagocytosis and ability to kill invading organisms is likely to enhance morbidity and mortality from infection in the postoperative period. Although volatile anaesthetic agents have been shown to influence the leucocyte function adversely, yet the effects of non-volatile anaesthetic agents and other allied drugs on the leucocyte phagocytic activity have not been explored. Therefore, the effects of premedicants (morphine, meperidine, diazepam), intravenous induction agents (thiopentone, methohexitone, alfathesin, and ketamine), local anaesthetic agents (lidocaine, procaine, and bupivacaine), muscle relaxants (succinylcholine and tubocurarine), and other drugs (prednisolone, furosemide, aspirin, epinephrine and chlorpromazine), on the phagocytic activity of leucocytes was investigated in vitro. |
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