Comparative toxicity of two ecdysteroid agonists, RH-2485 and RH-5992, on susceptible and pyrethroid-resistant strains of the Egyptian cotton leafworm,Spodoptera littoralis

Autor: Ishaaya, I., Yablonski, Sara, Horowitz, A. R.
Zdroj: Phytoparasitica; June 1995, Vol. 23 Issue: 2 p139-145, 7p
Abstrakt: The comparative toxicity of two non-steroidal ecdysteroid agonists, RH-2485 and RH-5992 (tebufenozide), on development stages, fecundity and egg viability of a susceptible laboratory strain and a pyrethroid-resistant field strain ofSpodoptera littoralis(Boisduval) was evaluated. Taking the LC50s as the criterion, RH-2485 was 3–7-fold more potent than RH-5992 against the susceptible and 7–14-fold more against the field strain. The LC50of RH-2485 in the 1st and 6th instars of the susceptible strain was 0.32 and 0.57 mg a.i./l, respectively. The field strain showed a mild cross-resistance of about threefold to both compounds in 1st instars and to a lesser extent in 6th instars. A considerable increase in fecundity (~3-fold) and no effect on egg viability was observed when 6th instars were fed on cotton leaves treated with 0.25 mg a.i./lRH-2485 (~LC40). Our results indicate that both compounds are potentially potent insecticides for controllingS. littoralislarvae, being 10-60-fold more potent than a previous ecdysteroid agonist, RH-5849.
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