Effect of Antibiotics, Sulfonamides, and a Nitrofuran on Development of Hepatic Cirrhosis in Choline-Deficient Rats

Autor: Salmon, W.D., Newberne, Paul M.
Zdroj: The Journal of Nutrition; April 1962, Vol. 76 Issue: 4 p483-491, 9p
Abstrakt: Penicillin G sodium, neomycin sulfate, oxytetracycline, sulfanilamide, sulfaguanidine, and furazolidone prevented or decreased the severity of hepatic cirrhosis in choline-deficient AES-strain rats over a 630-day test period. Penicillin or sulfanilamide did not prevent abnormal accumulation of lipids in livers of weanling rats subjected to acute choline deficiency; furthermore, they did not decrease incidence of hemorrhagic kidneys or mortality rates in such acutely deficient rats.
Databáze: Supplemental Index